Enable Write Cache on SATA Hard Drives:

Do you have a SATA disk drive in your computer, well guess what you can sweeze a little more performance out of it by enabling this tweak. This tweak speeds up the performance of your hard disk by enhancing write caching. However, if your computer is not connected to a battery backup and you loose power you have a increased risk for data loss or corruption. If you have a laptop your chances are data loss or corruption are dramatically less since your laptop battery will kick on if your power source is lost. So let’s get started:

1. Click on the Start Button and key in Device Manager and hit Enter.

2. Expand Disk Drives.

3. Right click on your hard drive and select Properties.

4. On the Policies tab, check Enable advanced performance.

Hit OK and close Device Manager. And Enjoy the added Performance

Aero tweak for Underpowered/Onboard Graphics:

This tip is pretty useful for notebook owners or anyone whose PC is packing graphics that are a little on the weak side. The Flip3D animation as we know can slow down weaker graphics cards if it has to flip a lot of windows, so this is a tweak that lets you set the number of windows that will be rendered in 3D at one time.

Click on the Start Button, type regedit in the Search bar, and press Enter.
Navigate to HKEY_CURRENT_USER\Software\Microsoft\Windows\DWM. Create a new DWORD and call it Max3DWindows.
Set the value of this to something between four and nine (“4” and “9”) depending on the performance of your card (a higher number requires more video card power). You should then feel free to experiment to find the best value for your computer. Restart your PC to finalize the change.

TCP Auto-Tuning:

To turn off the default RWIN auto tuning behavior, (in elevated command prompt) type:

netsh int tcp set global autotuninglevel=disabled

The default auto-tuning level is "normal", and the possible settings for the above command are:

disabled: uses a fixed value for the tcp receive window. Limits it to 64KB (limited at 65535).
higlyrestricted: allows the receive window to grow beyond its default value, very conservatively
restricted: somewhat restricted growth of the tcp receive window beyond its default value
normal: default value, allows the receive window to grow to accommodate most conditions
experimental: allows the receive window to grow to accommodate extreme scenarios (not recommended, it can degrade performance in common scenarios, only intended for research purposes. It enables RWIN values of over 16 MB)

Recommendation: normal  (unless you’re experiencing problems).

Useful Keyboard Shortcuts:

Keyboard shortcuts
Ctrl+Shift+Esc -> Task Manager (Ctrl+Alt+Del -> Tasks Screen)
Ctrl+Shift+Enter -> Run an executable with elevated privileges
Windows logo key+1-0 -> Launch the shortcuts on the Quick Launch toolbar
Windows logo key+T -> Cycle through programs on the taskbar
Windows logo key+Tab -> Cycle through programs on the taskbar by using Flip 3-D
Ctrl+Windows logo key+Tab -> Use the arrow keys to cycle through programs on the taskbar by using Flip 3-D
Windows logo key+Spacebar -> Bring all gadgets to the front and select Windows Sidebar
Windows logo key+G -> Cycle through Sidebar gadgets
Windows logo key+X -> Open Windows Mobility Center
Open a folder and press & release Alt -> Show Menu Bar (also works in Internet Explorer)

Enable DEP on Internet Explorer to protect against memory

Because browsers can host plug-in extensibility, security settings within the browser can make plug-ins fail. This is why in Internet Explorer 7 Data Execution Prevention (DEP) is off by default. Two of the most well-known and commonly used browser plug-ins, the Adobe Acrobat/Reader browser helper object and the Adobe Flash Player, now run when DEP is enabled. You can enable DEP by navigating to the following dialog and checking the highlighted option shown below (note, you must elevated to admin first, otherwise the option is grayed out).

Stay tuned guys as I bring you more of the best Windows Vista tips to help squeeze the most performance out of your PC.